CD11b antibody [ICRF44] (APC-Cy7)

Catalogue Number: GTX00481-15-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Molecular Weight:	127
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD11B , CR3A , ITGAM , MAC1 , MAC1A , MO1A , SLEB6 , integrin subunit alpha M , CD11b , Mac-1 , Macrophage 1 antigen
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	ICRF44
Isotype:	IgG1
Immunogen:	Rheumatoid synovial cells and human monocytes.
Application:	FC

Overview
Datasheets

Description

Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Additional Text

Gene Name

ITGAM

Gene ID

3684

Uniprot ID

P11215

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX00481-15 Datasheet

Price

£312.00

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Quantity
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