CD45R antibody [RA3-6B2]

Catalogue Number: GTX00486-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:145
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:protein tyrosine phosphatase, receptor type, C , B220 , CD45R , Cd45 , L-CA , Ly-5 , Lyt-4 , T200 , loc
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug
Host name: Rat
Clone: RA3-6B2
Isotype: IgG2a
Immunogen: Abelson murine leukemia virus-induced pre-B tumor cells
Application: FC, ICC, IF, IHC-P, IP, WB, IHC-Fr, Depl

Additional Text

Gene Name

PTPRC

Concentration

0.5 mg/ml

Uniprot ID

P06800

Purification

Affinity Purified

Molecular Weight

145

Gene ID

19264

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB, CD45RO and several others.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.