Mannose Receptor antibody [15-2] (PE)

Catalogue Number: GTX00491-08-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD206 , CLEC13D , CLEC13DL , MMR , MRC1 , MRC1L1 , bA541I19.1 , hMR , mannose receptor, C type 1 , Mannose Receptor , mrc1 , mannose receptor C-type 1
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: 15-2
Isotype: IgG1
Immunogen: Purified human mannose receptor
Application: FC, ICC, IF, IHC-P

Description

Description: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

Additional Text

Gene ID

4360

Gene Name

MRC1

Uniprot ID

P22897, Q5VSK2

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 10 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.