CTLA4 antibody [BNI3] (PE-Cy5)
Catalogue Number: GTX00492-09-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Molecular Weight: | 25 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | ALPS5 , CD , CD152 , CELIAC3 , CTLA4 , GRD4 , GSE , IDDM12 , cytotoxic Tlymphocyte associated protein 4 , cytotoxic T-lymphocyte associated protein 4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | BNI3 |
| Isotype: | IgG2a |
| Immunogen: | Human CD152-IgG heavy chain fusion protein |
| Application: | FC |
Description
Description: This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
Additional Text
Uniprot ID
P16410
Gene ID
1493
Gene Name
CTLA4
Antibody Clonality
Monoclonal
Purification
Size-exclusion Chromatography
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.
Application Notes
FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX00492-09 Datasheet
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