CD11c antibody [BU15] (PE-Cy7)
Catalogue Number: GTX00599-10-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Molecular Weight: | 128 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD11C , ITGAX , SLEB6 , integrin subunit alpha X , CD11c , Integrin alpha X |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | BU15 |
| Isotype: | IgG1 |
| Immunogen: | Dendritic cells of synovial fluid |
| Application: | FC |
Description
Description: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Additional Text
Gene Name
ITGAX
Uniprot ID
P20702
Gene ID
3687
Antibody Clonality
Monoclonal
Purification
Size-exclusion Chromatography
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.
Application Notes
FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX00599-10 Datasheet
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