CD3 epsilon antibody [145-2C11] (PE-Cy7)

Catalogue Number: GTX00603-10-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	21
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD3 antigen, epsilon polypeptide , AI504783 , CD3 , CD3epsilon , T3e
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Armenian Hamster
Clone:	145-2c11
Isotype:	IgG1
Immunogen:	Mouse BM10-37 cytotoxic T lymphocytes
Application:	FC

Overview
Datasheets

Additional Text

Gene Name

CD3E

Gene ID

12501

Concentration

0.2 mg/ml

Uniprot ID

P22646

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The 145-2C11 antibody is specific for mouse CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

GTX00603-10 Datasheet

GTX00603-10 Reference

Price

£293.00

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