GluR2 antibody
Catalogue Number: GTX00632-GTX
GTX00632 Image
GTX00632 Image
GTX00632 Image
GTX00632 Image
IHC-Fr analysis of rat cerebellum tissue using GTX00632 GluR2 antibody. Note that some GluA2 positive fibers (horizontal arrow) that are probable Bergmann glial processes do not stain for GluA2. Panel A : Co-localization of GluA2 (green) and calbindin D28-K (red) in Purkinje cell dendrites (vertical arrow). Panel B : Calbindin D28-K Panel C : GTX00632 Panel D : The molecular and Purkinje layer (blue).
GTX00632 Image
IP analysis of rat brain lysates using GTX00632 GluR2 antibody. Black arrow indicates the GluR2 protein while the red arrow shows the IgG heavy chain. Lane 1 : Primary antibody Lane 2 : Pre-immune rabbit serum Lane 3 : Input
GTX00632 Image
WB analysis of rat brain membrance lysates using GTX00632 GluR2 antibody. Lane 1 : Primary antibody Lane 2 : Primary antibody preincubated with the negative control antigen
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 99 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | glutamate ionotropic receptor AMPA type subunit 2 , GluA2 , GluR-K2 , GluR2 , gluR-B |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide NVGNINNDKKDETYR(C), corresponding to amino acid residues 179-193 of rat GluR2 (Accession P19491). Extracellular, N-terminus. |
| Application: | ICC, IF, IP, WB, IHC-Fr, LCImg |
Description
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
GRIA2
Concentration
0.6 mg/ml
Uniprot ID
P19491
Purification
Affinity Purified
Molecular Weight
99
Gene ID
29627
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX00632 Datasheet
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