CD19 antibody [HIB19] (PE-Cy7)

Catalogue Number: GTX01455-10-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	61
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD19 molecule , B4 , CD19 , CVID3
Shipping Condition:	Blue Ice
Unit(s):	100 tests
Host name:	Mouse
Clone:	HIB19
Isotype:	IgG1
Immunogen:
Application:	FC

Overview
Datasheets

Description

Description: Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

930

Uniprot ID

P15391

Concentration

0.05 mg/mL

Purification

Affinity Purified

Gene Name

CD19

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The HIB19 antibody reacts with human CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21, CD81 and CD225, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.The HIB19 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 0.25 µg (5 µl) for 10⁵-10⁸ cells in 100 µl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX01455-10 Datasheet

GTX01455-10 Reference

Price

£238.00

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