CD3 antibody [Hit3a]

Catalogue Number: GTX01459-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	CD3d molecule , CD3e molecule , CD3g molecule , CD247 molecule , CD3-DELTA , IMD19 , T3D , IMD18 , T3E , TCRE , CD3-GAMMA , IMD17 , T3G , CD3-ZETA , CD3H , CD3Q , CD3Z , IMD25 , T3Z , TCRZ
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	100 ug
Host name:	Mouse
Clone:	Hit3a
Isotype:	IgG2a
Immunogen:
Application:	FC, ICC, IF, IHC-Fr, NT, Inh, Act

Overview
Datasheets

Additional Text

Concentration

0.5 mg/ml

Purification

Affinity Purified

Antibody Clonality

Monoclonal

UniProt ID

P04234, P07766, P09693, P20963

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Gene Name

Cd247, Cd3d, Cd3e, Cd3g

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Gene ID

915; 916; 917; 919

Short Description

The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.The Hit3a antibody is a widely used phenotypic marker for human T cells. In addition, binding/cross-linking of Hit3a antibody to CD3e can induce cell activation. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

GTX01459 Datasheet

GTX01459 Reference

Price

£103.00

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