Integrin alpha 2 antibody [HMa2] (Biotin)

Catalogue Number: GTX01474-02-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:129
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Armenian Hamster
Clone: HMa2
Isotype: IgG
Immunogen:
Application: FC

Additional Text

Concentration

0.5 mg/ml

Gene ID

16398

Purification

Affinity Purified

Uniprot ID

Q62469

Gene Name

ITGA2

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin αfamily. CD49b, also known as integrin αalpha2, associates non-covalently with CD29 (integrin αbeta1) to form the VLA-2 heterodimer. VLA-2 integrin αs function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.