NCAM antibody [MY31] (PE-Cy7)

Catalogue Number: GTX01477-10-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:95
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:Neural Cell Adhesion Molecule 1 , Cd56 , Msk39 , Ncam , Ncam1
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MY31
Isotype: IgG1
Immunogen:
Application: FC

Description

Description: This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

Additional Text

Gene ID

4684

Uniprot ID

P13591

Concentration

0.1 mg/ml

Purification

Affinity Purified

Gene Name

NCAM1

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Short Description

The MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion. Clone MY31 also reacts with a subset of CD14+ monocytes in non-human primates, and is reported to be cross-reactive with Chimpanzee, Cynomolgus and Rhesus.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 0.5 µg (5 µl) for 10⁵-10⁸ cells in 100 µl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.