NK1.1 antibody [PK136]

Catalogue Number: GTX01478-GTX

Manufacturer:	GeneTex
Preservative:	0.09% sodium azide
Molecular Weight:	25
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	100 ug
Host name:	Mouse
Clone:	PK136
Isotype:	IgG2a
Immunogen:
Application:	FC, IHC-P, IP, IHC-Fr, NT, Inh, Depl, Act

Overview
Datasheets

Additional Text

Concentration

0.5 mg/ml

Gene ID

17059

Purification

Affinity Purified

Uniprot ID

P27814

Gene Name

Klrb1c

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1. The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

GTX01478 Datasheet

GTX01478 Reference

Price

£111.00

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