CD40L / CD154 antibody [MR1] (Biotin)

Catalogue Number: GTX01485-02-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:29
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Armenian Hamster
Clone: MR1
Isotype: IgG
Immunogen:
Application: FC

Additional Text

Gene ID

21947

Concentration

0.5 mg/ml

Uniprot ID

P27548

Purification

Affinity Purified

Gene Name

CD40LG

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between these cells. Signals generated via cognate interactions between CD154-CD40 on activated T and B cells are required for T-dependent B cell responses. The MR1 antibody is reported to block interaction of CD154 with CD40.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.