Peanut Lectin (Biotin)

Catalogue Number: GTX01507-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Physical state:Liquid
Type:Protein - Conjugated
Alias:Peanut Lectin , PNA , PNA lectin , Arachis hypogaea , Arachis hypogaea lectin , Peanut agglutinin lectin , Peanut agglutinin
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 1 mg
Host name:
Clone:
Isotype:
Immunogen:
Application: ELISA, WB, IHC

Description

Description: Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells. Peanut lectin contains one atom of Ca++ and Mg++ per unit. Inhibiting/Eluting sugars: 200 mM Galactose Carbohydrate-Binding Specificity of PNA: Galβ1, 3 GalNAc>>>>>GalNAc>Gal

Additional Text

Concentration

5 mg/ml

Purification

Affinity Purified

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:2500. ELISA: 1:500-1:2500. IHC: 1:250-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.