Peanut Lectin (PE)

Catalogue Number: GTX01509-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Physical state:Liquid
Type:Protein - Conjugated
Alias:Peanut Lectin , PNA , PNA lectin , Arachis hypogaea , Arachis hypogaea lectin , Peanut agglutinin lectin , Peanut agglutinin
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 500 ug
Host name:
Clone:
Isotype:
Immunogen:
Application: FC, ICC, IF

Description

Description: Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells. Peanut lectin contains one atom of Ca++ and Mg++ per unit. Inhibiting/Eluting sugars: 200 mM Galactose Carbohydrate-Binding Specificity of PNA: Galβ1, 3 GalNAc>>>>>GalNAc>Gal

Additional Text

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Short Description

Peanut lectin (PNA) is an identical tetrameric carbohydrate free protein with MW of 110 kDa. Thomsen-Friedenreich antigen, T-antigen (Galβ1, 3GalNAc) is present on blood group M &N glycoproteins (after removal of sialic acid with neuraminidase), glyconjugates (Mucin type), gangliosides and many glycolipids. T antigen is rarely expressed on normal coloncytes whereas cells of malignant, premalignant cells express this antigen. Peanut lectin has widely been used to detect T antigen in malignant and premalignant cells.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.

Application Notes

ICC/IF: 1:50-1:200. FCM: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.