Catalogue Number: GTX01512-GTX
Manufacturer: | GeneTex |
Preservative: | 0.05% Sodium azide |
Physical state: | Liquid |
Type: | Protein - Conjugated |
Alias: | UAE , Ulex europaeus , UAE I Lectin , Fucose lectin , UAE I , Ulex europaeus lectin , UAE Lectin |
Shipping Condition: | Blue Ice |
Storage Condition: | 2-8°C |
Unit(s): | 500 ug |
Application: | ICC, IF, IHC-P, IHC |
Description: The anti-H (O) hemagglutinating activity of Ulex europaeus has been used widely to confirm blood group O activity. UEA I binds to many glycoproteins and glycolipids containing α -linked fucose residue. The purified lectin appears to be a dimer of two distinct polypeptide chains associated by noncovalent forces. This lectin does not react with Lea active blood group substance. The native protein has pI=6.0-6.1 and exhibits a Molecular weight 60,000-68,000 during gel filtration on Sephadex column. This lectin will hemagglutinate fresh blood group O cells at 2-5µg/ml.Inhibiting/Eluting sugars: 50-100 mM L-fucoseCarbohydrate-Binding Specificity of UEA I: L-Fuα1,2Galβ1,4GlcNAcβ1,6R
1 mg/ml
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
The anti-H (O) hemagglutinating activity of Ulex europaeus has been used widely to confirm blood group O activity. UEA I binds to many glycoproteins and glycolipids containing α -linked fucose residue. The purified lectin appears to be a dimer of two distinct polypeptide chains associated by noncovalent forces. This lectin does not react with Lea active blood group substance. The native protein has pI=6.0-6.1 and exhibits a Molecular weight 60,000-68,000 during gel filtration on Sephadex column.