Human Autotaxin (mature) protein, His tag (active)

Catalogue Number: GTX02798-PRO-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Physical state:Liquid
Type:Other Enzymes
Alias:ectonucleotide pyrophosphatase/phosphodiesterase 2 , ATX , ATX-X , AUTOTAXIN , LysoPLD , NPP2 , PD-IALPHA , PDNP2
Host Cell:HEK293 cells
Shipping Condition:Dry Ice
Unit(s): 50 ug
Application: FA

Description

Description: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]

Additional Text

Gene ID

5168

Uniprot ID

Q13822

Protein Tag

HIS Tag

Gene Name

ENPP2

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

The reaction rate of GTX02798-pro Human Autotaxin (mature) protein (at different concentrations) were measured in FS-3 assay.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (at least 1 month), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.