Human IL4 protein, His tag (active)

Catalogue Number: GTX02862-PRO-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Physical state:	Liquid
Type:	Interleukins
Alias:	interleukin 4 , BCGF-1 , BCGF1 , BSF-1 , BSF1 , IL-4
Host Cell:	HEK293 cells
Shipping Condition:	Dry Ice
Unit(s):	50 ug
Application:	FA

Overview
Datasheets

Description

Description: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Additional Text

Uniprot ID

P05112

Gene ID

3565

Concentration

0.5 mg/ml

Accession Number

NP_000580

Protein Tag

HIS Tag

Gene Name

IL4

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Application Notes

Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED₅₀ range ≤ 0.5 ng/ml.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1 week), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX02862-PRO Datasheet

Price

£371.00

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Quantity
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