Human Folate Receptor beta protein, His tag

Catalogue Number: GTX02865-PRO-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Physical state:	Liquid
Type:	Other Proteins
Alias:	folate receptor beta , BETA-HFR , FBP , FBP/PL-1 , FR-BETA , FR-P3
Host Cell:	HEK293 cells
Shipping Condition:	Dry Ice
Unit(s):	50 ug
Application:	FA

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

2350

Uniprot ID

P14207

Concentration

0.25 mg/ml

Protein Tag

HIS Tag

Gene Name

FOLR2

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Accession Number

NP_000794.3

Application Notes

Binding assay: Measured by its binding ability in a functional ELISA with Folic Acid-BSA. The ED₅₀ range ≤ 5 µg/ml.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1 week), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX02865-PRO Datasheet

Price

£371.00

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Quantity
Unit Size

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