Human FAP protein, His tag (active)
Catalogue Number: GTX02866-PRO-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Physical state: | Liquid |
| Type: | Proteases |
| Alias: | fibroblast activation protein alpha , DPPIV , FAPA , FAPalpha , SIMP |
| Host Cell: | Baculovirus |
| Shipping Condition: | Dry Ice |
| Unit(s): | 50 ug |
| Application: | FA |
Description
Description: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Additional Text
Uniprot ID
Q12884
Gene ID
2191
Accession Number
NP_004451.2
Concentration
0.25 mg/ml
Protein Tag
HIS Tag
Gene Name
FAP
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Application Notes
Specific activity is > 5,000 pmol/min/µg, and is defined as the amount of enzyme that hydrolysis 1.0 pmole of Z-GP-AMC per minute at pH 7.5, at 37C.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1 week), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX02866-PRO Datasheet
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