IL12B / IL12 p40 antibody [MT618] (Biotin)
Catalogue Number: GTX02956-02-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 37 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CLMF,CLMF2,IL12B,IMD28,IMD29,NKSF,NKSF2,interleukin 12B,IL12 p40 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 250 ug |
| Host name: | Mouse |
| Clone: | MT618 |
| Isotype: | IgG1 |
| Immunogen: | Recombinant human IL-23 |
| Application: | ELISA, sELISA |
Description
Description: This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
Additional Text
Uniprot ID
P29460
Gene ID
3593
Concentration
0.5 mg/ml
Purification
Protein G purified
Gene Name
IL12B
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX02956-02 Datasheet
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