IL1 beta antibody [7P10] (Biotin)

Catalogue Number: GTX02971-02-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:31
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:IL1,IL1B,IL1BETA,IL1F2,interleukin 1 beta,IL1 beta,IL-1B
Shipping Condition:Blue Ice
Unit(s): 250 ug
Host name: Mouse
Clone: 7P10
Isotype: IgG2b
Immunogen: Recombinant human IL-1β
Application: ELISA, sELISA

Description

Description: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

3553

Uniprot ID

P01584

Concentration

0.5 mg/ml

Purification

Protein G purified

Gene Name

IL1B

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.