alpha Synuclein antibody [2A7]

Catalogue Number: GTX04298-GTX

Manufacturer:GeneTex
Preservative:5 mM Sodium azide
Molecular Weight:14
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:synuclein alpha , NACP , PARK1 , PARK4 , PD1
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 2A7
Isotype: IgG1
Immunogen: Full length human recombinant protein expressed in and purified from E. coli
Application: ICC, IF, WB, IHC-Flt

Description

Description: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

Additional Text

Gene ID

6622

Gene Name

SNCA

Uniprot ID

P37840

Purification

Purified

Antibody Clonality

Monoclonal

Molecular Weight

14

Concentration

1 mg/ml

Application Notes

WB: 1:1000. ICC/IF: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.