Mouse TGF beta 1 protein, His tag (active)

Catalogue Number: GTX04319-PRO-GTX

Manufacturer:	GeneTex
Preservative:	5% Proclin300
Molecular Weight:	14.1
Physical state:	Lyophilized
Type:	Transforming Growth Factors
Host Cell:	E.coli
Shipping Condition:	Blue Ice
Unit(s):	10 ug
Application:	WB, FA, NT, Inh

Overview
Datasheets

Description

Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016]

Additional Text

Uniprot ID

P04202

Gene Name

TGFB1

Gene ID

21803

Protein Tag

HIS Tag

Accession Number

NP_035707.1

Storage Note

Store at -20C or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.

GTX04319-PRO Datasheet

Price

£374.00

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