RPSA antibody [RPSA/2699]

Catalogue Number: GTX04349-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide\|0.05% Sodium azide
Molecular Weight:	33
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	ICAS,LAMBR,LAMR1,LBP,LBP/p40,LRP,LRP/LR,NEM/1CHD4,RPSA,SA,lamR,p40,ribosomal protein SA,37LRP,67LR,67kDa Laminin Receptor
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	RPSA/2699
Isotype:	IgG1
Immunogen:	Recombinant full-lengthhuman RPSA protein
Application:	FC, ICC, IF, IHC-P, WB, PA

Overview
Datasheets

Description

Description: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

3921

Gene Name

RPSA

Uniprot ID

P08865

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Molecular Weight

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1-2 µg/ml. ICC/IF: 1-2 µg/ml. IHC-P: 1-2 µg/ml. FCM: 1-2 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

GTX04349 Datasheet

Price

£504.00

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