CDH16 antibody [MSVA-516R] HistoMAX™

Catalogue Number: GTX04455-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:cadherin 16
Shipping Condition:Blue Ice
Unit(s): 100 ul, 500 ul
Host name: Rabbit
Clone: MSVA-516R
Isotype: IgG
Immunogen: Recombinant human full-length CDH16 protein
Application: IHC-P

Description

Description: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]

Additional Text

Gene Name

CDH16

Gene ID

1014

Uniprot ID

O75309

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Recombinant Monoclonal

Application Notes

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Price
£303.00


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