Occludin antibody [MSVA-415M] HistoMAX™
Catalogue Number: GTX04461-GTX
GTX04461 Image
GTX04461 Image
GTX04461 Image
GTX04461 Image
IHC-P analysis of human skin tissue using GTX04461 Occludin antibody [MSVA-415M] HistoMAX?. In squamous epithelium occludin positivity is regularly seen but staining is reduced or absent in basal and superficial cell layers scaled.
GTX04461 Image
IHC-P analysis of human lung tissue using GTX04461 Occludin antibody [MSVA-415M] HistoMAX?. Membranous occludin immunostaining of respiratory epithelium scaled.
GTX04461 Image
IHC-P analysis of human ovarian clear cell carcinoma (OCCC) tissue using GTX04461 Occludin antibody [MSVA-415M] HistoMAX?. Clear cell ovarian carcinoma with moderate occludin staining of tumor cells.
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide |
| Molecular Weight: | 59 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | occludin , BLCPMG , PPP1R115 , PTORCH1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 500 ul |
| Host name: | Mouse |
| Clone: | MSVA-415M |
| Isotype: | IgG1 |
| Immunogen: | ecombinant fragment of human Occludin protein (around aa 282-415) |
| Application: | IHC-P |
Description
Description: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
Additional Text
Gene Name
OCLN
Uniprot ID
Q16625
Gene ID
100506658
Purification
Protein A/G Purified
Concentration
0.2 mg/ml
Antibody Clonality
Monoclonal
Application Notes
IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX04461 Datasheet
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