Ku80 antibody [MSVA-880M] HistoMAX™

Catalogue Number: GTX04480-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	X-ray repair cross complementing 5 , KARP-1 , KARP1 , KU80 , KUB2 , Ku86 , NFIV
Shipping Condition:	Blue Ice
Unit(s):	100 ul, 500 ul
Host name:	Mouse
Clone:	MSVA-880M
Isotype:	IgG1, IgG2b
Immunogen:	Recombinant human XRCC5 fragmen
Application:	IHC-P

Overview
Datasheets

Description

Description: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

XRCC5

Uniprot ID

P13010

Gene ID

7520

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Application Notes

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

This antibody was validated on 76 different Normal Tissues by IHC-P.Go to Normal Tissue GalleryGo to Cancer Tissue Gallery

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX04480 Datasheet

Price

£303.00

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Quantity
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