Catalogue Number: GTX04532-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide |
| Molecular Weight: | 166 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | NLR family pyrin domain containing 1 , AIADK , CARD7 , CIDED , CLR17.1 , DEFCAP , DEFCAP-L/S , MSPC , NAC , NALP1 , PP1044 , SLEV1 , VAMAS1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | NALP1 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1. The immunogen is located within the last 50 amino acids of NALP1. |
| Application: | ELISA, ICC, IF, WB, IHC |
Description: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
NLRP1
22861
Q9C000
Affinity Purified
166
Polyclonal
1 mg/ml
WB: 1-4 µg/mL. ICC/IF: 20 µg/mL. IHC-P (cell pellet): 10 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.