NALP1 antibody

Catalogue Number: GTX04532-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide
Molecular Weight:166
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:NLR family pyrin domain containing 1 , AIADK , CARD7 , CIDED , CLR17.1 , DEFCAP , DEFCAP-L/S , MSPC , NAC , NALP1 , PP1044 , SLEV1 , VAMAS1
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: NALP1 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1. The immunogen is located within the last 50 amino acids of NALP1.
Application: ELISA, ICC, IF, WB, IHC

Description

Description: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

NLRP1

Gene ID

22861

Uniprot ID

Q9C000

Purification

Affinity Purified

Molecular Weight

166

Antibody Clonality

Polyclonal

Concentration

1 mg/ml

Application Notes

WB: 1-4 µg/mL. ICC/IF: 20 µg/mL. IHC-P (cell pellet): 10 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.