Human Wnt7a protein (active)

Catalogue Number: GTX04539-PRO-GTX

Manufacturer:GeneTex
Physical state:Lyophilized
Type:Other Proteins
Alias:Wnt family member 7A
Host Cell:HEK293 cells
Shipping Condition:Blue Ice
Unit(s): 15 ug
Application: FA

Description

Description: This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

WNT7A

Uniprot ID

O00755

Gene ID

7476

Accession Number

NP_004616.2

Application Notes

Determined by its ability to decrease alkaline phosphatase activity in CCL-226 cells when treated with 25 ng/ml of Murine Wnt-3a.

Storage Note

Store at -20C or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.