Adenosine A2a Receptor antibody [7F6-G5-A2]

Catalogue Number: GTX04561-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide
Molecular Weight:	45
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	adenosine A2a receptor , A2aR , ADORA2 , RDC8
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	7F6-G5-A2
Isotype:	IgG2a
Immunogen:	Full length recombinant human Adenosine A2a R(UniProt# P29274). Epitope mapped to SQPLPGER in the third intracellular loop (PMID 9822147).
Application:	FC, ICC, IF, IHC-P, WB, IHC-Fr, MC

Overview
Datasheets

Description

Description: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013]

Additional Text

Gene ID

135

Gene Name

ADORA2A

Uniprot ID

P29274

Purification

Protein G purified

Molecular Weight

Antibody Clonality

Monoclonal

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX04561 Datasheet

Price

£535.00

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