B3GALNT1 antibody [PA5]

Catalogue Number: GTX04882-GTX

Manufacturer:GeneTex
Preservative:No preservative
Molecular Weight:40
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:B3GALNT1,B3GALT3,GLCT3,GLOB,Gb4Cer,P,P1,beta1,3Nacetylgalactosaminyltransferase 1 (globoside blood group),beta3GalT3,galT3,beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: PA5
Isotype: IgM
Immunogen: Gb4Cer-labeled very long chain fatty acid (VLCFA)
Application: FC, ICC, IF, TLC

Description

Description: This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. [provided by RefSeq, Mar 2017]

Additional Text

Concentration

0.5 mg/ml

Gene ID

8706

Gene Name

B3GALNT1

Uniprot ID

O75752

Antibody Clonality

Monoclonal

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Purification

Purified by hydroxyapatite chromatography