CD16 antibody [KD1]
Catalogue Number: GTX04886-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 29|26 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Fc fragment of IgG receptor IIIa , Fc fragment of IgG receptor IIIb , CD16 , CD16A , FCG3 , FCGR3 , FCGRIII , FCR-10 , FCRIII , FCRIIIA , IGFR3 , IMD20 , CD16 , CD16A , CD16b , FCG3 , FCGR3 , FCGR3A , FCR-10 , FCRIII , FCRIIIb |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | KD1 |
| Isotype: | IgG2a |
| Immunogen: | A polyclonal population of NK cells. |
| Application: | FC, FA |
Description
Description: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Additional Text
Purification
Affinity Purified
Uniprot ID
O75015, P08637
Antibody Clonality
Monoclonal
Gene ID
2214; 2215
Gene Name
FCGR3A, FCGR3B
Concentration
1 mg/ml
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
FCM: 1:25-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX04886 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations