DDB1 antibody [N1N3]

Catalogue Number: GTX100129-GTX

Manufacturer:GeneTex
Preservative:0.01% Thimerosal
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:damage specific DNA binding protein 1 , DDBA , UV-DDB1 , XAP1 , XPCE , XPE , XPE-BF
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human DDB1. The exact sequence is proprietary.
Application: ICC, IF, WB

Description

Description: This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq]

Additional Text

Concentration

1 mg/ml

Gene Name

DDB1

Gene ID

1642

Purification

Affinity Purified

Molecular Weight

127

Uniprot ID

Q16531

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.