E-Cadherin antibody

Catalogue Number: GTX100443-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin™ 300
Molecular Weight:97
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:cadherin 1 , Arc-1 , BCDS1 , CD324 , CDHE , ECAD , LCAM , UVO
Shipping Condition:Dry Ice
Unit(s): 100 ul, 25 ul, 10 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human E-Cadherin. The exact sequence is proprietary.
Application: ICC, IF, IHC-P, IP, WB, IHC-WM

Description

Description: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq]

Additional Text

Gene Name

CDH1

Gene ID

999

Uniprot ID

P12830

Concentration

0.49 mg/ml

Molecular Weight

97

Price
223.00


Find out about delivery

SUPPORT

outstanding technical support

PRODUCT

we offer a full product guarantee

DELIVERY

we offer free delivery to UK universities and non profit organisations