HICE1 antibody
Catalogue Number: GTX100735-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.01% Thimerosal |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | HAUS augmin like complex subunit 8 , DGT4 , HICE1 , NY-SAR-48 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant protein corresponding to human HICE1 |
| Application: | ICC, IF, IHC-P, IP, WB |
Description
Description: HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM]
Additional Text
Gene Name
HAUS8
Uniprot ID
Q9BT25
Concentration
0.17 mg/ml
Purification
Affinity Purified
Gene ID
93323
Molecular Weight
45
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:50-1:500. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Short Description
HICE1 antibody recognizes HICE1 protein encoded by the human HAUS8 gene. HICE1 is a subunit of the microtubule-associated HAUS augmin-like complex, which is involved in maintenance of spindle integrity and microtubule nucleation during spindle assembly. Disruption of HICE1 results in abnormal spindle configuration, mitotic delay, and chromosomal instability.
GTX100735 Datasheet
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