POR antibody [N2C2], Internal

Catalogue Number: GTX101100-GTX

Manufacturer:GeneTex
Preservative:0.01% Thimerosal
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:cytochrome p450 oxidoreductase , CPR , CYPOR , P450R
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human POR. The exact sequence is proprietary.
Application: IHC-P, WB

Description

Description: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq]

Additional Text

Gene Name

POR

Uniprot ID

P16435

Concentration

0.75 mg/ml

Purification

Affinity Purified

Gene ID

5447

Molecular Weight

77

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.