beta Catenin antibody [N1N2-2], N-term

Catalogue Number: GTX101435-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin™ 300
Molecular Weight:85
Physical state:Liquid
Type:ChIP Validated Antibodies
Alias:catenin beta 1 , CTNNB , EVR7 , MRD19 , armadillo
Shipping Condition:Dry Ice
Unit(s): 100 ul, 25 ul, 10 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human beta Catenin. The exact sequence is proprietary.
Application: FACS, ICC, IF, IHC-P, IP, ChIP, WB

Description

Description: Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]

Additional Text

Gene Name

CTNNB1

Gene ID

1499

Uniprot ID

P35222

Concentration

0.1 mg/ml

Molecular Weight

85

Protein Target Region

N-terminus

Price
223.00


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