Cardiac Troponin I antibody [23C6]

Catalogue Number: GTX10229-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:24
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:troponin I3, cardiac type , CMD1FF , CMD2A , CMH7 , RCM1 , TNNC1 , cTnI
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 200 ug
Host name: Mouse
Clone: 23C6
Isotype: IgG2a
Immunogen: Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.
Application: AP, ELISA, IA, WB

Description

Description: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

7137

Gene Name

Tnni3

Uniprot ID

P19429

Molecular Weight

24

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.