TMS1 antibody [N1C3]

Catalogue Number: GTX102474-GTX

Manufacturer:GeneTex
Preservative:0.01% Thimerosal
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:PYD and CARD domain containing , ASC , CARD5 , TMS , TMS-1 , TMS1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human TMS1. The exact sequence is proprietary.
Application: ICC, IF, WB, IHC-Fr

Description

Description: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Additional Text

Concentration

1 mg/ml

Gene ID

29108

Gene Name

PYCARD

Uniprot ID

Q9ULZ3

Antibody Clonality

Polyclonal

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-Fr: Assay dependent. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Price
223.00


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