Catalogue Number: GTX103192-GTX
Manufacturer: | GeneTex |
Preservative: | 0.01% Thimerosal |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | RAN binding protein 1 , HTF9A |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 25 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Recombinant protein encompassing a sequence within the center region of human RanBP1. The exact sequence is proprietary. |
Application: | ICC, IF, WB |
Description: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq]
1 mg/ml
RANBP1
P43487
Affinity Purified
5902
Polyclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
23
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.