NRF2 antibody [N2C2], Internal

Catalogue Number: GTX103322-GTX

Manufacturer:GeneTex
Preservative:0.025% ProClin 300
Physical state:Liquid
Type:ChIP Validated Antibodies
Alias:nuclear factor, erythroid 2 like 2 , HEBP1 , IMDDHH , NRF2
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human NRF2. The exact sequence is proprietary.
Application: FACS, ICC, IF, IHC-P, IP, ChIP, WB

Description

Description: NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).[supplied by OMIM]

Additional Text

Gene Name

NFE2L2

Gene ID

4780

Uniprot ID

Q16236

Purification

Affinity Purified

Molecular Weight

68

Concentration

1.27 mg/ml

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

NRF2 antibody recognizes NRF2 protein, a basic leucine zipper region (bZip) transcription factor (predicted molecular weight of 68 kDa) that regulates expression of proteins with antioxidant and detoxification functions. NRF2 antibodies are commonly used to study oxidative stress, cell damage, metabolism, and immune response mechanisms, among others.