P2X7 antibody
Catalogue Number: GTX104288-GTX
GTX104288 Image
GTX104288 Image
GTX104288 Image
GTX104288 Image
P2X7 antibody detects P2X7 protein at cell membrane and cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. P2X7 antibody (GTX104288) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX104288 Image
P2X7 antibody detects P2X7 protein by immunohistochemical analysis. Sample: Frozen sectioned adult mouse retina. Green: P2X7 protein stained by P2X7 antibody (GTX104288) diluted at 1:250. Red: Protein kinase C alpha staining. Blue: Fluoroshield with DAPI (GTX30920). Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX104288 Image
Immunohistochemical analysis of paraffin-embedded human breast cancer, using P2X7(GTX104288) antibody at 1:250 dilution. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
| Manufacturer: | GeneTex |
| Preservative: | 0.01% Thimerosal|0.01% Thimerosal |
| Molecular Weight: | 69 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | purinergic receptor P2X 7 , P2X7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 25 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant protein encompassing a sequence within the center region of human P2X7. The exact sequence is proprietary. |
| Application: | IHC-P, IHC-Fr |
Description
Description: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
Additional Text
Gene Name
P2RX7
Uniprot ID
Q99572
Purification
Affinity Purified
Gene ID
5027
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Application Notes
IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX104288 Datasheet
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