NGF 2.5S antibody
Catalogue Number: GTX10515-GTX
| Manufacturer: | GeneTex |
| Preservative: | No preservative |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | nerve growth factor , Ngfb , beta-NGF |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | NGF-2.5S from male mouse submaxillary glands. |
| Application: | ICC, ID, IF, WB, DB, NT, Inh |
Description
Description: NGF is purified in three forms: the 7S, 2.5S and b. The 7S, 130 kDa, form occurs naturally in mouse submaxillary glands, and is a multimeric protein composed of two a, one b and two g subunits. The name is derived from its sedimentation co-efficient, 7S. The biologically active subunit is the b, which is a 26 kDa dimer composed of two identical 120 amino acid chains held together by hydrophobic interactions.5 The 2.5S form is 9 amino acids shorter than the b form, because of proteolysis that occurs during the purification process.6 The structural hallmark of all the neurotrophins is the characteristic arrangement of the disulfide bridges known as the cysteine knot, which has been found in other growth factors such as PDGF.
Additional Text
Gene Name
NGF
Uniprot ID
P01139
Gene ID
18049
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
27
Application Notes
WB: 1:2,000. Dot: 1:2,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Purification
Fractionated
GTX10515 Datasheet
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