TGF beta 1 antibody
Catalogue Number: GTX10518-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 44 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | transforming growth factor beta 1 , CED , DPD1 , IBDIMDE , LAP , TGFB , TGFbeta |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 ug |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | Recombinant human TGF-β1 expressed in CHO cells. |
| Application: | WB, NT, Inh |
Description
Description: Transforming Growth Factor Beta 1 is a multifunctional peptide capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed as well as non-neoplastic tissues, release transforming growth factors; and essentially all cells possess a specific TGF beta 1 receptor. The multi-modal nature of TGF beta 1 is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF-Beta-1 whereas hepatocytes, T and B lymphocytes, keratinocytes and many epithelial cells are inhibited by the peptide. TGF beta 1 interacts with Epidermal Growth Factor, Platelet Derived Growth Factor, Fibroblast Growth Factor, and IL2 either by enhancing or antagonizing their characteristic actions. TGF beta 1 plays a fundamental role in tissue growth and differentiation involvement in adipogenesis, myogenesis, chondrogenesis, osteogenesis, epithelial cell differentiation and immune cell function.
Additional Text
Gene ID
7040
Gene Name
TGFB1
Uniprot ID
P01137
Purification
Affinity Purified
Molecular Weight
44
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 0.1-0.2 µg/ml. Neutralizing/Inhibition: ND₅₀:5-30 ng/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX10518 Datasheet
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