Lymphotactin antibody

Catalogue Number: GTX10607-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	13
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	X-C motif chemokine ligand 1 , ATAC , LPTN , LTN , SCM-1 , SCM-1a , SCM1 , SCM1A , SCYC1
Shipping Condition:	Blue Ice
Unit(s):	25 ug
Host name:	Goat
Clone:
Isotype:	IgG
Immunogen:	purified recombinant human lymphotactin expressed in Escherichia coli.
Application:	ELISA, WB, NT, Inh

Overview
Datasheets

Description

Description: Human lymphotactin (Lptn)/XCL1, also named human SCM1 and ATAC, is a member of gamma or C subfamily of chemokines that lack two of the four invariant cysteine residues normally found in the CC and CXC chemokines and have an extended C-terminus. Human lymphotactin encodes a 114 amino acid precursor protein with a 21 amino acid predicted signal peptide. The gene for human and mouse lymphotactin has been mapped to chromosome 1. Human and mouse lymphotactin share approximately 60% amino acid sequence identity.The expression of lymphotactin is restricted to activated T cells such as activated CD8+ T cells and other class I MHC restricted T cells. Since lymphotactin is produced by lymphocytes and acts on lymphocytes, it is speculated that it is a messenger in T cell chemoattraction. Human lymphotactin is chemotactic for lymphocytes and NK cells. Its expression is abundant in some activated T cells such as activated CD8+ T cells and other class I MCH restricted T cells and is absent in CD4+ T cells. It has been shown that lymphotactin is a key regulator of lymphocyte motility and adhesion during acute allograft rejection. The specific receptor for lymphotactin is the orphan receptor XCR1 (GPR5).

Additional Text

Gene Name

XCL1

Uniprot ID

P47992

Gene ID

6375

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Application Notes

WB: 1-2 µg/ml. ELISA: 0.5-1.0 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX10607 Datasheet

Price

£499.00

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Quantity
Unit Size

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