Interferon gamma antibody
Catalogue Number: GTX10744-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 18 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | interferon gamma , IFNG2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | recombinant rat interferon-γ expressed in E. coli. |
| Application: | WB, IHC-Fr, NT, Inh |
Description
Description: Interferon gamma (IFNG), a type II or immune interferon, is produced primarily by T lymphocytes and natural killer cells stimulated by alloantigens, tumors, and mitogens. IFNG exerts a variety of biological effects including antiviral activity, inhibition of cell or tumor growth, and promotion of differentiation of B cells into immunoglobulin-producing cells. IFNG, originally characterized based on its antiviral activities, is a potent modulator of immune response and modifies cellular processes. It functions as an activating factor priming macrophages for non-specific tumorcidal activity. IFNG activates monocytes to exert enhanced cytotoxicity against tumor cells. It also boosts cytotoxicity of natural killer cells and stimulates T cell cytotoxicity. IFNG acts as a signal for the major histocompatibility antigen expression system. The species specificity of IFNG resides in the interaction of IFNG with its receptor. Mature IFNG exists as noncovalently linked homodimers. The N-terminal methionyl form of rat IFNG contains 135 amino acid residues and has a predicted molecular mass of approximately 15.5 kDa.
Additional Text
Uniprot ID
P01581
Gene Name
IFNG
Gene ID
25712
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
18
Application Notes
WB: 0.1-0.2 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX10744 Datasheet
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