IL1 beta antibody

Catalogue Number: GTX10750-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Molecular Weight:	31
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	interleukin 1 beta , IL-1beta , Il-1b
Shipping Condition:	Blue Ice
Unit(s):	500 ug
Host name:	Goat
Clone:
Isotype:	IgG
Immunogen:	recombinant mouse IL-1β.
Application:	WB, NT, Inh

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Additional Text

Uniprot ID

P10749

Gene Name

IL1B

Gene ID

16176

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Application Notes

WB: 1-2 µg/ml. Neutralizing/Inhibition: 50 pg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX10750 Datasheet

GTX10750 Reference

Price

£410.00

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Quantity
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