CD8 antibody [CA-8]
Catalogue Number: GTX10884-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.01 mg Sodium azide |
| Molecular Weight: | 26 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CD8a molecule , CD8 , Leu2 , p32 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | CA-8 |
| Isotype: | IgG2a |
| Immunogen: | Human thymocytes followed by peripheral blood T cells. |
| Application: | FC, ICC, IF, IHC-Fr |
Description
Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Additional Text
Gene ID
925
Gene Name
CD8A
Uniprot ID
P01732
Purification
Unpurified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
ICC/IF: 0.5-1µg/ml. IHC-Fr: 1µg/ml. FCM: 1-3µg/1x10⁶cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX10884 Datasheet
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