CYP7A1 antibody [N3C3]

Catalogue Number: GTX108871-GTX

Manufacturer:GeneTex
Preservative:0.01% Thimerosal|0.01% Thimerosal
Molecular Weight:58
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:cytochrome P450 family 7 subfamily A member 1 , CP7A , CYP7 , CYPVII
Shipping Condition:Blue Ice
Unit(s): 100 ul, 25 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human CYP7A1. The exact sequence is proprietary.
Application: WB

Description

Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. [provided by RefSeq]

Additional Text

Gene Name

CYP7A1

Uniprot ID

P22680

Gene ID

1581

Purification

Affinity Purified

Molecular Weight

58

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.